Michael Guo, MD, PhD

Michael Guo is an Assistant Professor in the Departments of Neurology and Genetics, and a clinician in the Penn Memory Center. He completed his PhD in genetics at Harvard and his MD at the University of Florida, followed by neurology residency at the University of Pennsylvania. He completed additional clinical fellowship and post-doctoral research training as a Clark Scholar in the Penn Memory Center, before joining as a faculty member in 2024. Clinically, he focuses on caring for patients with aging-related cognitive disorders such as Alzheimer’s disease. He also leads a research lab that is focused on understanding the genetics of Alzheimer’s disease and related dementias. His lab uses genetics as a tool  to identify the underlying causes of these diseases and develop more targeted therapies. His lab is also applying genetics to better predict risk and progression for Alzheimer’s disease and related dementias.